Information processing speed in multiple sclerosis: Relevance of default mode network dynamics

Default mode contributions to automated information processing.

Concurrent with mental processes that require rigorous computation and control, a series of automated decisions and actions govern our daily lives, providing efficient and adaptive responses to environmental demands. Using a cognitive flexibility task, we show that a set of brain regions collectively known as the default mode network plays a crucial role in such "autopilot" behavior, i.e., when...

Brain's Default Mode Network

Reentrant Information Flow in Electrophysiological Rat Default Mode Network

Functional MRI (fMRI) studies have demonstrated that the rodent brain shows a default mode network (DMN) activity similar to that in humans, offering a potential preclinical model both for physiological and pathophysiological studies. However, the neuronal mechanism underlying rodent DMN remains poorly understood. Here, we used electrophysiological data to analyze the power spectrum and estimat...

Default Mode Network (DMN) Activity during Olfactory Processing

Introduction: The dynamics of resting state networks during active and passive task performance has received increased attention in recent times [1, 2]. Several studies have reported modulations in the default mode network (DMN) (or deactivations) during the performance of sensoryand cognitivefMRI tasks [1, 2, 3]. However, no study has investigated such modulations in relation to olfaction. Usi...

Speed of information processing as a key deficit in multiple sclerosis: implications for rehabilitation.

Speed of information processing was assessed in patients with multiple sclerosis and healthy controls using both an auditory and visual task designed to control for accuracy of performance across groups. After controlling for accuracy of performance, patients with multiple sclerosis were found to have significantly slower speed of information processing relative healthy controls, irrespective o...